Nucleoporin Nup43 (NUP43) Antibody
169€ (20 µg)
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name
Nucleoporin Nup43 (NUP43) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx309716
tested applications
ELISA, WB, IHC
Description
NUP43 Antibody is a Rabbit Polyclonal against NUP43.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin Nup43 (NUP43) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFH3 |
| Gene ID | 348995 |
| NCBI Accession | NP_942590.1, NM_198887.2 |
| OMIM | 608141 |
| Alias | p42,bA350J20.1,Nucleoporin Nup43,Nup107-160 subcomplex subunit Nup45 |
| Background | Antibody anti-NUP43 |
| Status | RUO |
Descripción
Nucleoporin 43 (NUP43) is a component of the nuclear pore complex, which regulates the transport of molecules between the nucleus and the cytoplasm NUP43 is involved in maintaining the structural integrity of the nuclear pore and facilitating the transport of macromolecules, such as RNA and proteins, across the nuclear envelope It plays a role in both nuclear import and export, ensuring the proper functioning of cellular processes such as gene expression and cell cycle regulation Additionally, NUP43 is involved in the formation of the nuclear pore complex and interacts with other nucleoporins to maintain its stability Dysregulation of NUP43 has been linked to defects in nuclear transport, leading to a variety of diseases, including certain cancers and neurodegenerative disorders Its importance in cellular homeostasis underscores its essential role in maintaining proper nuclear-cytoplasmic communication
Related Products
Nucleoporin Nup43 (NUP43) Antibody
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).
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