Nucleoporin Nup43 (NUP43) Antibody
357.5€ (100 µg)
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Name
Nucleoporin Nup43 (NUP43) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx145464
Tested Applications
ELISA, WB
Description
NUP43 Antibody is a Rabbit Polyclonal against NUP43.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin Nup43 (NUP43) Immunogen: Recombinant fragment corresponding to 56-277 AA of human NUP43. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 42 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC065028 |
| Alias | p42,bA350J20.1,Nucleoporin Nup43,Nup107-160 subcomplex subunit Nup44 |
| Background | Antibody anti-NUP43 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 43 (NUP43) is a component of the nuclear pore complex, which regulates the transport of molecules between the nucleus and the cytoplasm NUP43 is involved in maintaining the structural integrity of the nuclear pore and facilitating the transport of macromolecules, such as RNA and proteins, across the nuclear envelope It plays a role in both nuclear import and export, ensuring the proper functioning of cellular processes such as gene expression and cell cycle regulation Additionally, NUP43 is involved in the formation of the nuclear pore complex and interacts with other nucleoporins to maintain its stability Dysregulation of NUP43 has been linked to defects in nuclear transport, leading to a variety of diseases, including certain cancers and neurodegenerative disorders Its importance in cellular homeostasis underscores its essential role in maintaining proper nuclear-cytoplasmic communication
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