Nucleoporin NUP35 (NUP53) Antibody
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Description
NUP53 Antibody is a Rabbit Polyclonal against NUP53.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin NUP35 (NUP53) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFH5 |
| Gene ID | 129401 |
| OMIM | 608140 |
| Alias | MP44,NP44,MP-44,NUP53,35 kDa nucleoporin,Mitotic phosphoprotein 44,Nucleoporin NUP53 |
| Background | Antibody anti-NUP35 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Nucleoporin 35 (NUP35) is a component of the nuclear pore complex, which serves as the gateway between the nucleus and the cytoplasm NUP35 plays an essential role in the structural integrity of the nuclear pore and in regulating the trafficking of molecules, particularly RNA and proteins, across the nuclear envelope As a nucleoporin, NUP35 participates in the formation of the nuclear pore complex, which facilitates selective transport and ensures proper cellular signaling and gene expression It also helps maintain nuclear-cytoplasmic communication, influencing cellular processes such as cell division, transcription, and gene regulation Dysregulation of NUP35 has been implicated in several diseases, including cancers and neurodegenerative disorders, where defective nuclear transport and nucleoporin function contribute to disease progression
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