Nucleoporin 35 (NUP35) Antibody

Este producto es parte de NUP - nucleoporin
Nucleoporin 35 (NUP35) Antibody
292.5€ (80 µl)

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Name
Nucleoporin 35 (NUP35) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx027067
Tested Applications
ELISA, WB, FCM

Description

This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is part of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Nucleoporin 35 (NUP35)
Immunogen: KLH-conjugated synthetic peptide between 289-318 amino acids from the C-terminal region of human NUP35.
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 34.8 kDa
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, FCM
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8NFH5
Alias
MP44,NP44,MP-44,NUP53,35 kDa nucleoporin,Mitotic phosphoprotein 44,Nucleoporin NUP53
Background
Antibody anti-NUP35
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Nucleoporin 35 (NUP35) is a component of the nuclear pore complex, which serves as the gateway between the nucleus and the cytoplasm NUP35 plays an essential role in the structural integrity of the nuclear pore and in regulating the trafficking of molecules, particularly RNA and proteins, across the nuclear envelope As a nucleoporin, NUP35 participates in the formation of the nuclear pore complex, which facilitates selective transport and ensures proper cellular signaling and gene expression It also helps maintain nuclear-cytoplasmic communication, influencing cellular processes such as cell division, transcription, and gene regulation Dysregulation of NUP35 has been implicated in several diseases, including cancers and neurodegenerative disorders, where defective nuclear transport and nucleoporin function contribute to disease progression

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