Nucleoporin 98 kDa (NUP98) Antibody
260€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Nucleoporin 98 kDa (NUP98) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx242361
Tested Applications
ELISA, WB
Description
NUP98 Antibody is a Rabbit Polyclonal against NUP98.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 98 kDa (NUP98) Immunogen: Synthetic peptide of human NUP98. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P52948 |
| Gene ID | 4928 |
| Alias | ADIR2,NUP96,NUP196,Nup98-96,Nuclear pore complex protein Nup98-Nup96, nucleoporin 96,ADAR2 |
| Background | Antibody anti-NUP98 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 98 and 96 precursor (NUP98) is an important member of the nuclear pore complex, involved in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP98 is part of the larger family of nucleoporins that help maintain the structural integrity and function of the nuclear pore complex, ensuring that proteins, RNA, and ribosomal subunits are efficiently transported across the nuclear envelope NUP98, in particular, is involved in the movement of RNA molecules from the nucleus to the cytoplasm, a critical step in gene expression and protein synthesis Additionally, NUP98 plays a role in the regulation of cell division and apoptosis, where it contributes to the proper functioning of the mitotic spindle and the cell cycle Dysregulation of NUP98 has been implicated in various cancers, where it contributes to the aberrant regulation of gene expression and the disruption of nuclear-cytoplasmic communication Mutations in NUP98 are also associated with hematological disorders such as leukemia, highlighting its significance in maintaining normal cellular processes and in disease progression Its role in both structural integrity and molecular trafficking makes NUP98 essential for cellular function and overall organismal health
Productos relacionados
Nucleoporin 98 (NUP98) Antibody
NUP98 Antibody is a Rabbit Polyclonal antibody against NUP98. Nup98-Nup96 (also known as Nup196, ADIR2 or ADAR2), encode…
Ver producto
Human Nucleoporin 98 kDa (NUP98) Protein
Human Nucleoporin 98 kDa (NUP98) is a recombinant Human protein expressed in E. coli.…
Ver producto
Mouse Nucleoporin 98 kDa (NUP98) Protein
Mouse Nucleoporin 98 kDa (NUP98) is a recombinant Mouse protein expressed in E. coli.…
Ver producto