Mouse Nucleoporin 98 kDa (NUP98) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein NUP98
proveedor
Abbexareference
abx068370Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Nucleoporin 98 kDa (NUP98) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Nucleoporin 98 and 96 precursor (NUP98) is an important member of the nuclear pore complex, involved in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP98 is part of the larger family of nucleoporins that help maintain the structural integrity and function of the nuclear pore complex, ensuring that proteins, RNA, and ribosomal subunits are efficiently transported across the nuclear envelope NUP98, in particular, is involved in the movement of RNA molecules from the nucleus to the cytoplasm, a critical step in gene expression and protein synthesis Additionally, NUP98 plays a role in the regulation of cell division and apoptosis, where it contributes to the proper functioning of the mitotic spindle and the cell cycle Dysregulation of NUP98 has been implicated in various cancers, where it contributes to the aberrant regulation of gene expression and the disruption of nuclear-cytoplasmic communication Mutations in NUP98 are also associated with hematological disorders such as leukemia, highlighting its significance in maintaining normal cellular processes and in disease progression Its role in both structural integrity and molecular trafficking makes NUP98 essential for cellular function and overall organismal health
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Nucleoporin 98kDa (NUP98)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 26.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr568-Tyr776 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP98
dry ice
No
availability
Shipped within 5-7 working days.
alias
ADIR2,NUP96,NUP196,Nup98-96,Nuclear pore complex protein Nup98-Nup96, nucleoporin 96,ADAR2
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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