Nucleoporin 85 (NUP85) Antibody
357.5€ (100 µg)
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name
Nucleoporin 85 (NUP85) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122131
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the NUP85 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 85 (NUP85) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC000697 |
| Alias | Nup75,FROUNT,NPHS17,nucleoporin 85kDa,Nuclear pore complex protein Nup85,Nucleoporin Nup75,Nucleoporin Nup85,Pericentrin-1 |
| Background | Antibody anti-NUP85 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Nucleoporin 85 (NUP85) is a key structural component of the nuclear pore complex, critical for regulating the transport of large macromolecules, such as RNA and proteins, between the nucleus and cytoplasm NUP85 is involved in maintaining the architecture of the nuclear pore, ensuring that molecular trafficking is highly selective and efficient It participates in both nuclear import and export processes by forming part of the pore's central channel and interacting with various transport factors that help shuttle molecules across the nuclear envelope NUP85 plays an important role in gene expression regulation, RNA processing, and protein synthesis by facilitating the movement of factors that control these cellular processes Dysregulation of NUP85 expression or function can lead to a variety of diseases, including cancer, where defects in nucleocytoplasmic transport contribute to altered gene expression and defective cellular processes NUP85 also has a role in cellular responses to environmental stress, helping to maintain the stability of the nucleus and ensuring proper cellular functioning during stress and repair processes By supporting key signaling pathways and the maintenance of cellular integrity, NUP85 plays a critical role in both normal cellular activities and in the prevention of diseases like cancer, making it an important regulator of cellular homeostasis
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