Nucleoporin 85 kDa (NUP85) Antibody
273€ (100 µl)
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Name
Nucleoporin 85 kDa (NUP85) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx128760
Tested Applications
WB, IHC
Description
Nucleoporin 85 kDa Antibody is a Rabbit Polyclonal against Nucleoporin 85 kDa.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 85 kDa (NUP85) Immunogen: NUP85 (Arg130-Leu368) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Nup75,FROUNT,NPHS17,nucleoporin 85kDa,Nuclear pore complex protein Nup85,Nucleoporin Nup75,Nucleoporin Nup85,Pericentrin-1 |
| Background | Antibody anti-NUP85 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 85 (NUP85) is a key structural component of the nuclear pore complex, critical for regulating the transport of large macromolecules, such as RNA and proteins, between the nucleus and cytoplasm NUP85 is involved in maintaining the architecture of the nuclear pore, ensuring that molecular trafficking is highly selective and efficient It participates in both nuclear import and export processes by forming part of the pore's central channel and interacting with various transport factors that help shuttle molecules across the nuclear envelope NUP85 plays an important role in gene expression regulation, RNA processing, and protein synthesis by facilitating the movement of factors that control these cellular processes Dysregulation of NUP85 expression or function can lead to a variety of diseases, including cancer, where defects in nucleocytoplasmic transport contribute to altered gene expression and defective cellular processes NUP85 also has a role in cellular responses to environmental stress, helping to maintain the stability of the nucleus and ensuring proper cellular functioning during stress and repair processes By supporting key signaling pathways and the maintenance of cellular integrity, NUP85 plays a critical role in both normal cellular activities and in the prevention of diseases like cancer, making it an important regulator of cellular homeostasis
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