Nucleoporin 62 C-Terminal Like (NUP62CL) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Nucleoporin 62 C-Terminal Like (NUP62CL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx235928
tested applications
ELISA, WB
Description
NUP62CL Antibody is a Rabbit Polyclonal against NUP62CL.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 62 C-Terminal Like (NUP62CL) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H1M0 |
| Gene ID | 54830 |
| Alias | NUP62L,nucleoporin 62kDa C-terminal like |
| Background | Antibody anti-NUP62CL |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Nucleoporin 62 C-Terminal Like (NUP62CL) is a protein homologous to the C-terminal domain of NUP62, a key component of the nuclear pore complex (NPC). The NPC is crucial for nucleocytoplasmic transport, facilitating the selective exchange of macromolecules such as RNA and proteins between the nucleus and cytoplasm. While the specific role of NUP62CL is less defined, it is thought to contribute to NPC-associated processes, potentially influencing transport dynamics or structural integrity of the pore complex. Emerging evidence suggests that NUP62CL may have tissue-specific or context-dependent functions, possibly in specialized forms of transport regulation or in the assembly of nuclear pores under specific conditions. Dysregulation of nucleoporins, including NUP62CL, has been implicated in diseases such as cancer and neurodegenerative disorders, highlighting the importance of NPC components in maintaining cellular homeostasis. Further research is needed to uncover the precise biological and pathological roles of NUP62CL.
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