Human Nucleoporin 35 kDa (NUP35) Protein
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Description
Nucleoporin 35 kDa Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nucleoporin 35kDa (NUP35) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 23.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr132-Lys310 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFH5 |
| Alias | MP44,NP44,MP-44,NUP53,35 kDa nucleoporin,Mitotic phosphoprotein 44,Nucleoporin NUP53 |
| Background | Protein NUP35 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleoporin 35 (NUP35) is a component of the nuclear pore complex, which serves as the gateway between the nucleus and the cytoplasm NUP35 plays an essential role in the structural integrity of the nuclear pore and in regulating the trafficking of molecules, particularly RNA and proteins, across the nuclear envelope As a nucleoporin, NUP35 participates in the formation of the nuclear pore complex, which facilitates selective transport and ensures proper cellular signaling and gene expression It also helps maintain nuclear-cytoplasmic communication, influencing cellular processes such as cell division, transcription, and gene regulation Dysregulation of NUP35 has been implicated in several diseases, including cancers and neurodegenerative disorders, where defective nuclear transport and nucleoporin function contribute to disease progression
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