Nucleoporin 210 kDa / gp210 (NUP210) Antibody
292.5€ (80 µl)
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935106861
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name
Nucleoporin 210 kDa / gp210 (NUP210) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034590
tested applications
ELISA, WB, IHC, FCM
Description
NUP210 nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 210 kDa / gp210 (NUP210) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000, IHC-P: 1/500, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TEM1 |
| Alias | GP210,POM210,nucleoporin 210kDa,Nuclear pore membrane glycoprotein 210 |
| Background | Antibody anti-NUP210 |
| Status | RUO |
Descripción
Nucleoporin 210 (NUP210) is a member of the nuclear pore complex that plays a vital role in the regulation of macromolecular trafficking between the nucleus and cytoplasm NUP210 is involved in the structure and assembly of the nuclear pore, where it contributes to the formation of the central pore channel that allows the selective passage of RNA and proteins across the nuclear envelope It also participates in the regulation of cellular processes such as gene expression, cell cycle progression, and DNA repair by ensuring the proper exchange of factors necessary for these processes NUP210 is particularly important during cell division, where it helps maintain nuclear envelope integrity and supports the organization of the mitotic spindle Dysregulation of NUP210 expression has been associated with diseases such as cancer, where defects in nucleocytoplasmic transport contribute to tumor cell survival, resistance to apoptosis, and metastasis Its involvement in cellular signaling, division, and stress responses underscores its critical role in maintaining overall cellular function and stability
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