Nucleoporin 155 (NUP155) Antibody
195€ (20 µl)
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935106861
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name
Nucleoporin 155 (NUP155) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx007057
tested applications
ELISA, WB
Description
NUP155 Antibody is a Rabbit Polyclonal Antibody against NUP155.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 155 (NUP155) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75694 |
| Gene ID | 9631 |
| NCBI Accession | NP_705618.1 |
| Alias | N155,ATFB15,nucleoporin 155kDa,Nuclear pore complex protein Nup155 |
| Background | Antibody anti-NUP155 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Nucleoporin 155 (NUP155) is a critical member of the nuclear pore complex, involved in regulating the passage of macromolecules between the nucleus and cytoplasm NUP155 interacts with other nucleoporins to form part of the pore's central channel, which is essential for the selective transport of proteins, RNA, and ribosomal subunits NUP155 has a vital role in maintaining nuclear-cytoplasmic communication, influencing processes like gene expression and cellular stress responses It is also implicated in the regulation of mitosis, ensuring the proper exchange of factors necessary for cell division and chromosome segregation Dysregulation of NUP155 is associated with cancer, where defects in nucleocytoplasmic transport contribute to uncontrolled cell division and tumor progression Furthermore, NUP155 is involved in the stability of the nuclear envelope and may play a role in cellular responses to DNA damage and oxidative stress, making it a key player in maintaining cellular integrity and function
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