Human Nucleoporin 155 kDa (NUP155) Protein

234€ (10 µg)
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name
Human Nucleoporin 155 kDa (NUP155) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168258
tested applications
WB, SDS-PAGE
Description
Nucleoporin 155 kDa Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Nucleoporin 155kDa (NUP155) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 29.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln1154-Asn1379 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O75694 |
Alias | N155,ATFB15,nucleoporin 155kDa,Nuclear pore complex protein Nup155 |
Background | Protein NUP155 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nucleoporin 155 (NUP155) is a critical member of the nuclear pore complex, involved in regulating the passage of macromolecules between the nucleus and cytoplasm NUP155 interacts with other nucleoporins to form part of the pore's central channel, which is essential for the selective transport of proteins, RNA, and ribosomal subunits NUP155 has a vital role in maintaining nuclear-cytoplasmic communication, influencing processes like gene expression and cellular stress responses It is also implicated in the regulation of mitosis, ensuring the proper exchange of factors necessary for cell division and chromosome segregation Dysregulation of NUP155 is associated with cancer, where defects in nucleocytoplasmic transport contribute to uncontrolled cell division and tumor progression Furthermore, NUP155 is involved in the stability of the nuclear envelope and may play a role in cellular responses to DNA damage and oxidative stress, making it a key player in maintaining cellular integrity and function
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