Human Nucleoporin 155 kDa (NUP155) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein NUP155
proveedor
Abbexareference
abx168258Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Nucleoporin 155 kDa Protein is a recombinant Human protein expressed in E. coli.
Background
Nucleoporin 155 (NUP155) is a critical member of the nuclear pore complex, involved in regulating the passage of macromolecules between the nucleus and cytoplasm NUP155 interacts with other nucleoporins to form part of the pore's central channel, which is essential for the selective transport of proteins, RNA, and ribosomal subunits NUP155 has a vital role in maintaining nuclear-cytoplasmic communication, influencing processes like gene expression and cellular stress responses It is also implicated in the regulation of mitosis, ensuring the proper exchange of factors necessary for cell division and chromosome segregation Dysregulation of NUP155 is associated with cancer, where defects in nucleocytoplasmic transport contribute to uncontrolled cell division and tumor progression Furthermore, NUP155 is involved in the stability of the nuclear envelope and may play a role in cellular responses to DNA damage and oxidative stress, making it a key player in maintaining cellular integrity and function
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Nucleoporin 155kDa (NUP155)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 29.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln1154-Asn1379 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP155
dry ice
No
availability
Shipped within 5-7 working days.
alias
N155,ATFB15,nucleoporin 155kDa,Nuclear pore complex protein Nup155
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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