Mouse Nucleoporin 107 kDa (NUP107) Protein

Este producto es parte de NUP - nucleoporin
Mouse Nucleoporin 107 kDa (NUP107) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein NUP107

proveedor

Abbexa

reference

abx068355

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Nucleoporin 107 kDa (NUP107) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Nucleoporin 107 (NUP107) is an integral part of the nuclear pore complex, where it plays a crucial role in the assembly and function of the pore NUP107 interacts with other nucleoporins to form the central scaffold of the pore, contributing to the selective passage of molecules, such as RNA and proteins, between the nucleus and cytoplasm NUP107 is also involved in the regulation of the cell cycle and DNA repair by ensuring proper nuclear-cytoplasmic exchange of cell cycle regulators and repair proteins Its function is critical for maintaining cellular homeostasis, as defects in nucleocytoplasmic transport can lead to diseases such as cancer and neurodegenerative disorders Dysregulation of NUP107 has been linked to increased susceptibility to genetic instability, tumor formation, and poor prognosis in several cancers Additionally, NUP107 plays a role in the maintenance of the nuclear envelope, supporting nuclear structure and stability during cell division

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Nucleoporin 107kDa (NUP107)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 30.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu554-Thr784 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

NUP107


dry ice

No


availability

Shipped within 5-7 working days.


alias

ODG6,NUP84,NPHS11,ODG6,GAMOS7,nucleoporin 107kDa,nuclear pore complex protein Nup107


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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