Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1) Antibody
357.5€ (100 µg)
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Name
Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx122665
Tested Applications
ELISA, WB
Description
Rabbit Polyclonal against the NR2C1 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1) Immunogen: Recombinant fragment corresponding to 47-221 AA of human NR2C1. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 67 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC040141 |
| Alias | TR2,Orphan nuclear receptor TR2,Testicular receptor 2 |
| Background | Antibody anti-NR2C1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as TR2, is a nuclear receptor that is involved in regulating various biological processes, including development, metabolism, and cellular differentiation NR2C1 is expressed in a variety of tissues, including the brain, liver, and reproductive organs, where it plays a role in regulating the expression of genes involved in lipid metabolism, steroidogenesis, and cellular growth It functions by binding to specific DNA sequences and modulating the transcription of target genes, influencing both developmental processes and the regulation of metabolic pathways NR2C1 also plays a role in the regulation of the immune system, where it helps control the expression of genes involved in immune responses and inflammation Dysregulation of NR2C1 has been associated with disorders such as cancer, where altered nuclear receptor activity can contribute to tumor progression and metastasis Additionally, NR2C1 is implicated in the regulation of circadian rhythms and reproductive health, highlighting its importance in maintaining cellular and systemic homeostasis Its involvement in development, metabolism, and immune function positions NR2C1 as a potential therapeutic target for diseases related to hormonal imbalances, inflammation, and cancer
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