Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Antibody
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Description
Nuclear Receptor Subfamily 2, Group C, Member 1 Antibody is a Rabbit Polyclonal antibody against Nuclear Receptor Subfamily 2, Group C, Member 1.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13056 |
| Gene ID | 7181 |
| NCBI Accession | NP_001027458.1, NM_001032287.2, NP_001120834.1, NM_001127362.1, NP_003288.2, NM_003297.3 |
| OMIM | 601529 |
| Alias | TR2,Orphan nuclear receptor TR2,Testicular receptor 2 |
| Background | Antibody anti-NR2C1 |
| Status | RUO |
Descripción
Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as TR2, is a nuclear receptor that is involved in regulating various biological processes, including development, metabolism, and cellular differentiation NR2C1 is expressed in a variety of tissues, including the brain, liver, and reproductive organs, where it plays a role in regulating the expression of genes involved in lipid metabolism, steroidogenesis, and cellular growth It functions by binding to specific DNA sequences and modulating the transcription of target genes, influencing both developmental processes and the regulation of metabolic pathways NR2C1 also plays a role in the regulation of the immune system, where it helps control the expression of genes involved in immune responses and inflammation Dysregulation of NR2C1 has been associated with disorders such as cancer, where altered nuclear receptor activity can contribute to tumor progression and metastasis Additionally, NR2C1 is implicated in the regulation of circadian rhythms and reproductive health, highlighting its importance in maintaining cellular and systemic homeostasis Its involvement in development, metabolism, and immune function positions NR2C1 as a potential therapeutic target for diseases related to hormonal imbalances, inflammation, and cancer
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