NRG1 isoform-10 Antibody
Pida mas información
935106861
info@markelab.com
Precio
43.75€ (10 µg)
Antibody anti-NRG1
proveedor
Abbexareference
abx013109Tested Applications
WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Rabbit polyclonal antibody against NRG1 isoform-10 protein. Immunogen region is N-terminal.
Background
Neuregulin 1 (NRG1) is a pivotal signaling protein within the neuregulin family, recognized for its extensive roles in mediating cell-cell communication across various tissues, particularly the nervous system, cardiac muscle, and epithelial structures. This protein functions as a ligand for ErbB receptor tyrosine kinases, thereby regulating processes such as neuronal differentiation, synaptic development, and myelination of nerve fibers. In cardiac tissue, NRG1 is indispensable for heart development and plays a role in maintaining the function and repair of adult cardiac cells. Dysregulation of NRG1 signaling pathways has been linked to a range of pathological conditions, including schizophrenia, various types of cancer, and heart disease, underscoring its biological and therapeutic importance.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
NRG1 isoform-10
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC
purification
Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
buffer
PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
size 1
10 µg
size 2
100 µg
size 3
200 µg
size 4
300 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
NRG1
dry ice
No
availability
Shipped within 5-10 working days.
alias
GGF,HGL,HRG,NDF,ARIA,GGF2,HRG1,HRGA,SMDF,MST131,MSTP131,NRG1-IT2,Pro-NRG1,Pro-neuregulin-1 membrane-bound isoform,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45
note
This product is for research use only.
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