Nexilin (NEXN) Antibody
286€ (100 µl)
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name
Nexilin (NEXN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx177803
tested applications
WB, IHC, IF/ICC
Description
Nexilin (NEXN) Antibody is a Rabbit Polyclonal antibody against Nexilin (NEXN).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nexilin (NEXN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q0ZGT2 |
| Gene ID | 91624 |
| OMIM | 613121 |
| Alias | CMH20,NELIN,F-actin-binding protein |
| Background | Antibody anti-NEXN |
| Status | RUO |
| Note | Concentration: 0.72 mg/ml - |
Descripción
Nexilin, encoded by the NEXN gene, is a crucial protein involved in the maintenance and regulation of the actin cytoskeleton. It was first identified through its interaction with F-actin, an essential component of the cytoskeleton, which is involved in various cellular processes including shape maintenance, motility, and intracellular transport. Nexilin is highly expressed in cardiac muscle cells and skeletal muscle cells, highlighting its importance in the function and integrity of muscle tissues. The protein is essential for normal cardiac function and structural integrity, making it a significant player in cardiac health and disease.
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