Human Nexilin (NEXN) Protein
208€ (10 µg)
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name
Human Nexilin (NEXN) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654557
tested applications
WB, SDS-PAGE
Description
Human Nexilin (NEXN) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Nexilin (NEXN) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 43.7 kDa Observed MW: 45 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu409-Val605 Tag: His and TRxA Tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q0ZGT2 |
| Gene ID | 91624 |
| OMIM | 613121 |
| Alias | CMH20,NELIN,F-actin-binding protein |
| Background | Protein NEXN |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Nexilin, encoded by the NEXN gene, is a crucial protein involved in the maintenance and regulation of the actin cytoskeleton. It was first identified through its interaction with F-actin, an essential component of the cytoskeleton, which is involved in various cellular processes including shape maintenance, motility, and intracellular transport. Nexilin is highly expressed in cardiac muscle cells and skeletal muscle cells, highlighting its importance in the function and integrity of muscle tissues. The protein is essential for normal cardiac function and structural integrity, making it a significant player in cardiac health and disease.
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