Neurotrophic Tyrosine Kinase Receptor Type 3 (NTRK3) Antibody

Descripción

NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues.This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position.Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.