Mouse Ntrk3 Antibody
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935106861
info@markelab.com
Precio
281.25€ (80 µl)
Antibody anti-NTRK3
proveedor
Abbexareference
abx028185Tested Applications
ELISA, WB, IHCreactivity
Mousestatus
RUOclonality
PolyclonalDescripción
Ntrk3 is a receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).
Background
Neurotrophic receptor tyrosine kinase 3 (NTRK3), also known as TrkC, binds primarily with neurotrophin-3 (NT-3) and is integral to the proper development and function of both the central and peripheral nervous systems. This receptor promotes neuronal survival, axonal growth, and the guidance of neuronal connections during development. Dysfunctions in NTRK3 signaling pathways are linked to developmental disorders, including autism spectrum disorders and some cancers, such as medulloblastomas. Its role in neurodevelopment and oncology continues to be a focus of significant clinical research.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Mouse
immunogen target
Mouse Ntrk3
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
NTRK3
dry ice
No
availability
Shipped within 5-10 working days.
alias
TRKC,GP145-TrkC,gp145(trkC),TrkC tyrosine kinase,Neurotrophic tyrosine kinase receptor type 3,NT-3 growth factor receptor
uniprot id
note
This product is for research use only.
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