Neurotensin Receptor 2 (NTSR2) Antibody (FITC)

Este producto es parte de NTSR - Neurotensin Receptor
Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Neurotensin Receptor 2 (NTSR2) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx336806

Description

NTSR2 Antibody (FITC) is a Rabbit Polyclonal against NTSR2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Neurotensin Receptor 2 (NTSR2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O95665
Gene ID
23620
Alias
NTSR2,NTR2,levocabastine-sensitive neurotensin receptor,NTR2,high-affinity levocabastine-sensitive neurotensin receptor,neurotensin receptor type 2,NT2R
Background
Antibody anti-NTSR2
Status
RUO

Descripción

NTSR2 is a G protein-coupled receptor for neurotensin (NT), with lower affinity compared to NTSR1. NTSR2 is expressed in the central nervous system, including the spinal cord, midbrain, and peripheral tissues, where it regulates pain perception, neurotransmission, and immune responses. NTSR2 primarily couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neuronal excitability and neurotransmitter release. NTSR2 plays a key role in antinociception, particularly in modulating chronic and neuropathic pain pathways. Compared to NTSR1, NTSR2’s effects are more focused on pain relief and anti-inflammatory responses, making it a promising target for analgesic therapies. Dysregulation of NTSR2 signaling is associated with chronic pain conditions and neuroinflammation. Selective NTSR2 agonists are being investigated for their potential to treat pain without the side effects associated with opioid analgesics. NTSR2’s role in pain modulation and inflammation positions it as a critical therapeutic target for analgesia and neuroimmune regulation.

Related Products

abx152563

Human Neurotensin Receptor 2 (NTSR2) ELISA Kit

Human Neurotensin Receptor 2 (NTSR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neurotensin Receptor 2 (NTSR2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neurotensin Receptor 2 (NTSR2)

Ver Producto
abx212094

Neurotensin Receptor 2 (NTSR2) Antibody

NTSR2 Antibody is a Rabbit Polyclonal against NTSR2.

Ver Producto
abx329543

Neurotensin Receptor 2 (NTSR2) Antibody

NTSR2 Antibody is a Rabbit Polyclonal against NTSR2.

Ver Producto