Human Neurotensin Receptor 2 (NTSR2) ELISA Kit
715€ (96 tests)
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name
Human Neurotensin Receptor 2 (NTSR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152563
tested applications
ELISA
Description
Human Neurotensin Receptor 2 (NTSR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neurotensin Receptor 2 (NTSR2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neurotensin Receptor 2 (NTSR2)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neurotensin Receptor 2 (NTSR2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O95665 |
| Gene ID | 23620 |
| OMIM | 605538 |
| Alias | NTSR2,NTR2,levocabastine-sensitive neurotensin receptor,NTR2,high-affinity levocabastine-sensitive neurotensin receptor,neurotensin receptor type 2,NT2R |
| Background | Elisa kits for NTSR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NTSR2 is a G protein-coupled receptor for neurotensin (NT), with lower affinity compared to NTSR1. NTSR2 is expressed in the central nervous system, including the spinal cord, midbrain, and peripheral tissues, where it regulates pain perception, neurotransmission, and immune responses. NTSR2 primarily couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neuronal excitability and neurotransmitter release. NTSR2 plays a key role in antinociception, particularly in modulating chronic and neuropathic pain pathways. Compared to NTSR1, NTSR2’s effects are more focused on pain relief and anti-inflammatory responses, making it a promising target for analgesic therapies. Dysregulation of NTSR2 signaling is associated with chronic pain conditions and neuroinflammation. Selective NTSR2 agonists are being investigated for their potential to treat pain without the side effects associated with opioid analgesics. NTSR2’s role in pain modulation and inflammation positions it as a critical therapeutic target for analgesia and neuroimmune regulation.
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