Human Neurotensin Receptor 2 (NTSR2) ELISA Kit

Name: Human Neurotensin Receptor 2 (NTSR2) ELISA Kit
Brand: Abbexa
SKU: abx152563
Price: 715 EUR
Availability: OnlineOnly

Este producto es parte de NTSR - Neurotensin Receptor

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NTSR2

proveedor

Abbexa

reference

abx152563

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Neurotensin Receptor 2 (NTSR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neurotensin Receptor 2 (NTSR2) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Neurotensin Receptor 2 (NTSR2)

Background

NTSR2 is a G protein-coupled receptor for neurotensin (NT), with lower affinity compared to NTSR1. NTSR2 is expressed in the central nervous system, including the spinal cord, midbrain, and peripheral tissues, where it regulates pain perception, neurotransmission, and immune responses. NTSR2 primarily couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neuronal excitability and neurotransmitter release. NTSR2 plays a key role in antinociception, particularly in modulating chronic and neuropathic pain pathways. Compared to NTSR1, NTSR2’s effects are more focused on pain relief and anti-inflammatory responses, making it a promising target for analgesic therapies. Dysregulation of NTSR2 signaling is associated with chronic pain conditions and neuroinflammation. Selective NTSR2 agonists are being investigated for their potential to treat pain without the side effects associated with opioid analgesics. NTSR2’s role in pain modulation and inflammation positions it as a critical therapeutic target for analgesia and neuroimmune regulation.

Características del producto

immunogen target

Neurotensin Receptor 2 (NTSR2)

reactivity

Human

test range

0.156 ng/ml - 10 ng/ml

sensitivity

< 0.07 ng/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Tissue homogenates and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

NTSR2,NTR2,levocabastine-sensitive neurotensin receptor,NTR2,high-affinity levocabastine-sensitive neurotensin receptor,neurotensin receptor type 2,NT2R

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

NTSR2

dry ice

uniprot id

https://www.uniprot.org/uniprotkb/O95665

gene id

https://www.ncbi.nlm.nih.gov/gene/23620

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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