Neuropeptide Y Receptor Y5 (NPY5R) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Neuropeptide Y Receptor Y5 (NPY5R) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx329436
tested applications
ELISA, WB, IHC, IF/ICC
Description
NPY5R Antibody is a Rabbit Polyclonal against NPY5R.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuropeptide Y Receptor Y5 (NPY5R) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15761 |
| Gene ID | 4889 |
| Alias | NPY5R,NPY5-R,NPYY5-R,ood intake receptor,neuropeptide Y receptor type 5 |
| Background | Antibody anti-NPY5R |
| Status | RUO |
Descripción
NPY5R is a G protein-coupled receptor that binds neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is primarily expressed in the hypothalamus and limbic system, where it regulates appetite, energy homeostasis, and stress responses. NPY5R couples to Gi/o proteins, inhibiting adenylate cyclase and reducing cAMP levels, leading to modulation of neuronal signaling and feeding behavior. Activation of NPY5R promotes appetite stimulation and energy storage, playing a critical role in obesity and metabolic disorders. NPY5R also contributes to stress-related behaviors, anxiety, and cardiovascular regulation. Dysregulation of NPY5R signaling is associated with hyperphagia, obesity, and mood disorders. NPY5R antagonists are being explored as therapeutic agents to suppress appetite and reduce body weight in obesity. Its involvement in feeding behavior, stress regulation, and energy balance highlights NPY5R as a potential target for treating obesity, metabolic syndrome, and related mood disorders.
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