Neuronal Growth Regulator 1 (NEGR1) Antibody
292.5€ (80 µl)
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935106861
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name
Neuronal Growth Regulator 1 (NEGR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029178
tested applications
ELISA, WB
Description
NEGR1 may be involved in cell-adhesion. May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuronal Growth Regulator 1 (NEGR1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z3B1 |
| Alias | Ntra,KILON,IGLON4,DMML2433,IgLON family member 4 |
| Background | Antibody anti-NEGR1 |
| Status | RUO |
Descripción
Neuronal Growth Regulator 1 (NEGR1) is a glycosylphosphatidylinositol (GPI)-anchored protein that plays a critical role in brain development, particularly in processes involving cell adhesion, synapse formation, and neuronal connectivity. It is a member of the immunoglobulin superfamily and is predominantly expressed in the central nervous system. NEGR1 contributes to neuronal growth and synaptic plasticity, influencing cognitive functions such as learning and memory. It is also implicated in regulating neuronal migration and axon guidance during development. Variants or altered expression of NEGR1 have been associated with neuropsychiatric conditions, including autism spectrum disorders, schizophrenia, and depression, underlining its importance in maintaining normal brain function. As a potential biomarker and therapeutic target, NEGR1 continues to be a focus of research in neurodevelopmental and psychiatric disease studies.
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