Neurofascin (NFASC) Antibody

Background

Neurofascin (NFASC) is a cell adhesion molecule crucial for the development and maintenance of the nervous system. It is part of the L1 family of cell adhesion molecules, which are integral membrane proteins involved in cell-cell adhesion processes. Neurofascin plays a pivotal role in the formation and function of the nodes of Ranvier and the initial segments of axons, both of which are critical for the proper conduction of electrical impulses along neurons. The NFASC gene, located on chromosome 1q32.1, encodes several isoforms of neurofascin through alternative splicing. These isoforms have distinct but overlapping functions in neural development and synaptic plasticity.