Human Neurofascin (NFASC) Protein
234€ (10 µg)
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Name
Human Neurofascin (NFASC) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx068240
Tested Applications
WB, SDS-PAGE
Description
Human Neurofascin (NFASC) is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Neurofascin (NFASC) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asn760-Ala1007 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 28.3 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | O94856 |
| Alias | NF,NRCAML,NEDCPMD,KIAA0756 |
| Background | Protein NFASC |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
Neurofascin (NFASC) is a cell adhesion molecule crucial for the development and maintenance of the nervous system. It is part of the L1 family of cell adhesion molecules, which are integral membrane proteins involved in cell-cell adhesion processes. Neurofascin plays a pivotal role in the formation and function of the nodes of Ranvier and the initial segments of axons, both of which are critical for the proper conduction of electrical impulses along neurons. The NFASC gene, located on chromosome 1q32.1, encodes several isoforms of neurofascin through alternative splicing. These isoforms have distinct but overlapping functions in neural development and synaptic plasticity.
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