Neuregulin-1 (Nrg1) Antibody

Este producto es parte de NRG - neuregulin
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637€ (100 µl)

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935106861
info@markelab.com
name
Neuregulin-1 (Nrg1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx114063
tested applications
ELISA, WB, IHC

Description

Neuregulin-1 (Nrg1) Antibody is a Rabbit Polyclonal antibody against Neuregulin-1 (Nrg1).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetNeuregulin-1 (Nrg1)
HostRabbit
ReactivityHuman, Mouse
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationAntigen Affinity Chromatography.
Size 1100 µl
FormLiquid
Tested ApplicationsELISA, WB, IHC
BufferPBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ02297
Gene ID3084
NCBI AccessionNM_013964.4
OMIM142445
AliasGGF,HGL,HRG,NDF,ARIA,GGF2,HRG1,HRGA,SMDF,MST131,MSTP131,NRG1-IT2,Pro-NRG1,Pro-neuregulin-1 membrane-bound isoform,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45
BackgroundAntibody anti-NRG1
StatusRUO

Descripción

Neuregulin 1 (NRG1) is a pivotal signaling protein within the neuregulin family, recognized for its extensive roles in mediating cell-cell communication across various tissues, particularly the nervous system, cardiac muscle, and epithelial structures. This protein functions as a ligand for ErbB receptor tyrosine kinases, thereby regulating processes such as neuronal differentiation, synaptic development, and myelination of nerve fibers. In cardiac tissue, NRG1 is indispensable for heart development and plays a role in maintaining the function and repair of adult cardiac cells. Dysregulation of NRG1 signaling pathways has been linked to a range of pathological conditions, including schizophrenia, various types of cancer, and heart disease, underscoring its biological and therapeutic importance.

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