Neuregulin-1 (Nrg1) Antibody

Este producto es parte de NRG - neuregulin
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637€ (100 µl)

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935106861
info@markelab.com
name
Neuregulin-1 (Nrg1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx114063
tested applications
ELISA, WB, IHC

Description

Neuregulin-1 (Nrg1) Antibody is a Rabbit Polyclonal antibody against Neuregulin-1 (Nrg1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Neuregulin-1 (Nrg1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q02297
Gene ID
3084
NCBI Accession
NM_013964.4
OMIM
142445
Alias
GGF,HGL,HRG,NDF,ARIA,GGF2,HRG1,HRGA,SMDF,MST131,MSTP131,NRG1-IT2,Pro-NRG1,Pro-neuregulin-1 membrane-bound isoform,Acetylcholine receptor-inducing activity,Breast cancer cell differentiation factor p45
Background
Antibody anti-NRG1
Status
RUO

Descripción

Neuregulin 1 (NRG1) is a pivotal signaling protein within the neuregulin family, recognized for its extensive roles in mediating cell-cell communication across various tissues, particularly the nervous system, cardiac muscle, and epithelial structures. This protein functions as a ligand for ErbB receptor tyrosine kinases, thereby regulating processes such as neuronal differentiation, synaptic development, and myelination of nerve fibers. In cardiac tissue, NRG1 is indispensable for heart development and plays a role in maintaining the function and repair of adult cardiac cells. Dysregulation of NRG1 signaling pathways has been linked to a range of pathological conditions, including schizophrenia, various types of cancer, and heart disease, underscoring its biological and therapeutic importance.

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