Myosin-Binding Protein H (MYBPH) Antibody

Este producto es parte de MYBPH - myosin binding protein H ( LIKE)
Myosin-Binding Protein H (MYBPH) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-MYBPH

proveedor

Abbexa

reference

abx029727

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

MYBPH binds to myosin; probably involved in interaction with thick myofilaments in the A-band.


Background

Myosin Binding Protein H (MYBPH) is a member of the myosin-binding protein family, which are crucial for regulating muscle contraction and sarcomere organization in striated muscles. MYBPH primarily interacts with thick filaments, specifically the myosin filaments, contributing to the stabilization and structural integrity of the sarcomere, the fundamental contractile unit of muscle fibers. Structurally, MYBPH contains immunoglobulin-like (Ig-like) domains, which facilitate its binding to myosin and other sarcomeric proteins. These domains allow MYBPH to regulate the alignment and interaction of thick filaments within the sarcomere. MYBPH is primarily expressed in striated muscles, particularly in cardiac and skeletal muscles, suggesting its role in maintaining the functional architecture of these tissues. Functionally, MYBPH plays a role in modulating muscle contraction and fine-tuning sarcomere mechanics. By interacting with myosin heavy chains, MYBPH can influence the efficiency and stability of actomyosin interactions during contraction. Mutations or alterations in MYBPH expression have been linked to certain muscle disorders, including cardiomyopathies and other skeletal muscle dysfunctions, where sarcomere disorganization occurs.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Myosin-Binding Protein H (MYBPH)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified through a protein A column, followed by peptide affinity purification.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

MYBPH


dry ice

No


availability

Shipped within 5-10 working days.


alias

MyBP-H,H-protein


note

This product is for research use only.


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proveedor

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reference

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Tested Applications

ELISA, WB

reactivity

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status

RUO

clonality

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proveedor

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reference

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Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Polyclonal

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