Myosin-Binding Protein H-Like (MYBPHL) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Myosin-Binding Protein H-Like (MYBPHL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx048493
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the MYBPHL protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myosin-Binding Protein H-Like (MYBPHL) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | A2RUH7 |
| Gene ID | 343263 |
| NCBI Accession | BC132902 |
| Alias | MYBPHL |
| Background | Antibody anti-MYBPHL |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Myosin Binding Protein H-like (MYBPHL) is a protein closely related to MYBPH but exhibits distinct structural and functional features. MYBPHL also contains immunoglobulin-like (Ig-like) domains, which are critical for binding myosin and organizing the sarcomere structure. However, its expression pattern is more tissue-specific compared to MYBPH. MYBPHL is predominantly found in skeletal muscle and may also have a role in cardiac tissues under certain conditions. MYBPHL is believed to contribute to thick filament stabilization and fine-tuning of muscle contractility, similar to MYBPH, but its specific role in sarcomere dynamics and muscle contraction remains less well-defined. Emerging research indicates that MYBPHL may be involved in muscle development and adaptation to stress or injury, particularly during increased mechanical loading or pathological conditions. MYBPHL is being investigated as a potential marker for certain muscle-related diseases, including myopathies and cardiomyopathies, due to its structural similarities to other sarcomeric proteins.
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