Myelin Associated Glycoprotein (MAG) Antibody
312€ (60 µl)
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935106861
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name
Myelin Associated Glycoprotein (MAG) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005421
tested applications
IHC
Description
MAG Antibody is a Rabbit Polyclonal antibody against MAG. The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Myelin Associated Glycoprotein (MAG) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20916 |
| Gene ID | 4099 |
| Alias | GMA,S-MAG,SPG75,SIGLEC4,SIGLEC4A,SIGLEC-4A |
| Background | Antibody anti-MAG |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein that plays a crucial role in the nervous system. It is predominantly found in the myelin sheath, a protective covering that surrounds nerve fibers (axons) in both the central nervous system (CNS) and the peripheral nervous system (PNS). MAG is essential for the maintenance of myelin integrity, axon-myelin interactions, and the regulation of axonal growth and regeneration. It belongs to the immunoglobulin superfamily, which is characterized by the presence of immunoglobulin-like domains. MAG's functions are vital for proper neuronal signaling and overall nervous system health.
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