Family main features
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein that plays a crucial role in the nervous system. It is predominantly found in the myelin sheath, a protective covering that surrounds nerve fibers (axons) in both the central nervous system (CNS) and the peripheral nervous system (PNS). MAG is essential for the maintenance of myelin integrity, axon-myelin interactions, and the regulation of axonal growth and regeneration. It belongs to the immunoglobulin superfamily, which is characterized by the presence of immunoglobulin-like domains. MAG's functions are vital for proper neuronal signaling and overall nervous system health.
MAG is a complex protein with a distinct structure that enables its various functions:
MAG is part of the immunoglobulin superfamily, specifically within the subgroup of myelin-associated proteins. There are no distinct subtypes of MAG; however, it exists in two isoforms generated by alternative splicing:
These isoforms are expressed in different proportions during development and in different regions of the nervous system, suggesting specialized roles.
MAG has several critical functions in the nervous system:
Alterations in MAG expression or function have been linked to several neurological disorders and conditions:
Myelin Associated Glycoprotein (MAG) is a pivotal protein in the nervous system, integral to the formation, maintenance, and function of the myelin sheath. Its structure, consisting of immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail, enables it to mediate critical interactions between myelin and axons. MAG's functions include maintaining myelin integrity, regulating axon-myelin interactions, and inhibiting axonal growth, which are essential for proper neural function. However, its role in inhibiting axonal regeneration poses challenges in conditions such as multiple sclerosis, peripheral neuropathies, traumatic brain injury, and spinal cord injury. Understanding MAG's functions and mechanisms is crucial for developing therapeutic strategies to address these conditions and promote neural repair and regeneration.
myelin associated glycoprotein (MAG)
GMA,S-MAG,SPG75,SIGLEC4,SIGLEC4A,SIGLEC-4A
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, Primary Antibodies, CLIA Kits, ELISA Kits) relacionados con MAG - myelin associated glycoprotein
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Esta página contiene 29 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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FineTest | MAG | EH3319 | Human MAG Ab(Anti-Myelin Associated Glycoprotein Antibody) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antigen | 0.313-20ng/ml | 96T | RUO | |||
FineTest | MAG | EH0897 | Human MAG(Myelin-associated glycoprotein) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | P20916 | RUO | ||
Abbexa | MAG | abx195700 | Human Myelin Associated Glycoprotein (MAG) CLIA Kit | Human | Serum, plasma and other biological fluids. | Sandwich | 62.5 pg/ml - 4000 pg/ml | 37.5 pg/ml | 618.75 | 96 tests | RUO | |
Abbexa | MAG | abx491474 | Human Myelin Associated Glycoprotein (MAG) CLIA Kit | Human | Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.112 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MAG | abx152257 | Human Myelin Associated Glycoprotein (MAG) ELISA Kit | Human | Tissue homogenates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.12 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | MAG | abx253853 | Human Myelin Associated Glycoprotein (MAG) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | 0.19 ng/ml | 562.5 | 96 tests | P20916 | RUO |
Abbexa | MAG | abx512912 | Mouse Myelin-associated glycoprotein (MAG) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.156 ng/ml - 10 ng/ml | < 0.088 ng/ml | 687.5 | 96 tests | P20917 | RUO |
Abbexa | MAG | abx491475 | Rat Myelin Associated Glycoprotein (MAG) CLIA Kit | Rat | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.129 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | MAG | abx155796 | Rat Myelin Associated Glycoprotein (MAG) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | MAG | abx570800 | Rat Myelin Associated Glycoprotein (MAG) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 78 pg/ml - 5000 pg/ml | 46.9 pg/ml | 587.5 | 96 tests | P07722 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | MAG | FNab04932 | anti- MAG antibody | human | polyclonal | Rabbit | myelin associated glycoprotein | IgG | Unconjugated | ELISA, WB | 100µg | P20916 | RUO | |
Abbexa | MAG | abx370591 | Myelin Associated Glycoprotein (MAG) Antibody Pair | Human | Myelin Associated Glycoprotein (MAG) | ELISA | 1325 | 5 × 96 tests | RUO | |||||
Abbexa | MAG | abx128701 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | WB, IHC, IF/ICC | 250 | 100 µl | P20916 | RUO | |
Abbexa | MAG | abx173644 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Monoclonal | Mouse | Myelin Associated Glycoprotein (MAG) | Unconjugated | WB, IHC, IF/ICC | 712.5 | 1 ml | RUO | ||
Abbexa | MAG | abx105688 | Myelin Associated Glycoprotein (MAG) Antibody (Biotin) | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Biotin | ELISA | 162.5 | 20 µg | P20916 | RUO | |
Abbexa | MAG | abx336621 | Myelin Associated Glycoprotein (MAG) Antibody (HRP) | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | HRP | ELISA | 162.5 | 20 µg | P20916 | RUO | |
Abbexa | MAG | abx128702 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | WB, IHC, IF/ICC | 250 | 100 µl | P20916 | RUO | |
Abbexa | MAG | abx107105 | Myelin Associated Glycoprotein (MAG) Antibody (FITC) | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | FITC | 162.5 | 20 µg | P20916 | RUO | ||
Abbexa | MAG | abx214750 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P20916 | RUO | |
Abbexa | MAG | abx110016 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | ELISA, WB, IHC, IF/ICC | 162.5 | 20 µg | P20916 | RUO | |
Abbexa | MAG | abx214749 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | ELISA, WB, IHC | 250 | 50 µl | P20916 | RUO | |
Abbexa | MAG | abx005421 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | WB | 175 | 20 µl | P20916 | RUO | |
Abbexa | MAG | abx234932 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | ELISA, WB | 350 | 100 µg | P20916 | RUO | |
Abbexa | MAG | abx327468 | Myelin Associated Glycoprotein (MAG) Antibody | Human | Polyclonal | Rabbit | Myelin Associated Glycoprotein (MAG) | Unconjugated | ELISA, WB | 187.5 | 50 µg | P20916 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | MAG | abx691949 | Mouse Myelin Associated Glycoprotein (MAG) Protein | Mouse | Recombinant | HEK293 cells | SDS-PAGE | 325 | 20 µg | RUO | ||
Abbexa | MAG | abx166493 | Human Myelin Associated Glycoprotein (MAG) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | RUO | |
Abbexa | MAG | abx654422 | Rat Myelin Associated Glycoprotein (MAG) Protein | Rat | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 200 | 10 µg | RUO | |
Abbexa | MAG | abx166496 | Human Myelin Associated Glycoprotein (MAG) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | P20916 | RUO |
Abbexa | MAG | abx690994 | Mouse Myelin Associated Glycoprotein (MAG) Protein | Mouse | Recombinant | HEK293 cells | SDS-PAGE | 912.5 | 100 µg | RUO |
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