Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) Antibody
260€ (50 µl)
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935106861
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name
Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx212322
tested applications
ELISA, WB
Description
MADCAM1 Antibody is a Rabbit Polyclonal against MADCAM1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13477 |
| Gene ID | 8174 |
| Background | Antibody anti-MADCAM1 |
| Status | RUO |
Descripción
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MADCAM1 antibody
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
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