Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) Antibody
195€ (20 µl)
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935106861
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name
Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx007221
tested applications
ELISA, WB, IHC
Description
MADCAM1 Antibody is a Rabbit Polyclonal Antibody against MADCAM1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Mucosal Addressin Cell Adhesion Molecule 1 (MADCAM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/200 - 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13477 |
| Gene ID | 8174 |
| NCBI Accession | NP_570116.2 |
| Background | Antibody anti-MADCAM1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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MADCAM1 antibody
Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
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