Mouse Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx525984
tested applications
ELISA
Description
Mouse Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Uracil nucleotide/cysteinyl leukotriene receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6NS65 |
| Gene ID | 574402 |
| Alias | GPR17,P2Y-like receptor,UDP/CysLT receptor,R12,uracil nucleotide/cysteinyl leukotriene receptor |
| Background | Elisa kits for GPR17 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
GPR17 is a G protein-coupled receptor involved in several physiological processes, including the regulation of myelination, neurotransmitter release, and inflammation. GPR17 has been identified as a receptor that is expressed in oligodendrocyte precursor cells and plays a role in myelin formation in the central nervous system. GPR17 is activated by both endogenous ligands, such as uracil nucleotides, and can also respond to purines like adenosine. Upon activation, GPR17 primarily couples to Gi and Gq proteins, leading to intracellular signaling that influences cellular processes such as differentiation and migration. Dysregulation of GPR17 has been linked to neurodegenerative diseases, including multiple sclerosis, where it may impact myelin repair and regeneration. Investigating GPR17 signaling could provide new therapeutic strategies for neurodegenerative disorders and conditions that involve impaired tissue repair.
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