Mouse Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GPR17
proveedor
Abbexareference
abx525984Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Uracil nucleotide/cysteinyl leukotriene receptor (GPR17) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Uracil nucleotide/cysteinyl leukotriene receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
GPR17 is a G protein-coupled receptor involved in several physiological processes, including the regulation of myelination, neurotransmitter release, and inflammation. GPR17 has been identified as a receptor that is expressed in oligodendrocyte precursor cells and plays a role in myelin formation in the central nervous system. GPR17 is activated by both endogenous ligands, such as uracil nucleotides, and can also respond to purines like adenosine. Upon activation, GPR17 primarily couples to Gi and Gq proteins, leading to intracellular signaling that influences cellular processes such as differentiation and migration. Dysregulation of GPR17 has been linked to neurodegenerative diseases, including multiple sclerosis, where it may impact myelin repair and regeneration. Investigating GPR17 signaling could provide new therapeutic strategies for neurodegenerative disorders and conditions that involve impaired tissue repair.
Características del producto
category
ELISA Kits
immunogen target
Uracil nucleotide/cysteinyl leukotriene receptor (GPR17)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
GPR17,P2Y-like receptor,UDP/CysLT receptor,R12,uracil nucleotide/cysteinyl leukotriene receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GPR17
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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