Mouse Tyrosine-Protein Kinase Receptor UFO (AXL) Protein
1118€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Mouse Tyrosine-Protein Kinase Receptor UFO (AXL) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx691915
Tested Applications
SDS-PAGE
Description
Mouse Axl Kinase Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met 1-Pro 443) of mouse AXL (NP_033491.2) precursor was fused with a polyhistidine tag at the C-terminus.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Axl Kinase |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Pro443 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 47.8 kDa |
| Expression | Recombinant |
| Purity | > 98% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_033491.2 |
| Alias | ARK,UFO,AXL3,JTK11,Tyro7,AXL oncogene,Tyrosine-protein kinase receptor UFO |
| Background | Protein AXL |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
AXL receptor tyrosine kinase (AXL) is a member of the TAM (Tyro3, AXL, and MERTK) receptor tyrosine kinase family. This family of receptors is characterized by their roles in cell survival, proliferation, migration, and immune regulation. AXL was first identified as a transforming gene in chronic myeloid leukemia, and since then, it has been implicated in a variety of physiological and pathological processes, including cancer, fibrosis, and immune response modulation. AXL and its ligands are widely expressed in various tissues, including the cardiovascular, immune, and nervous systems. The primary ligand for AXL is growth arrest-specific 6 (Gas6), a vitamin K-dependent protein that mediates the receptor's activation. Binding of Gas6 to AXL triggers a cascade of downstream signaling events that influence cellular behaviors and fate decisions.
Productos relacionados
Tyrosine-Protein Kinase Receptor UFO (AXL) Antibody
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other …
Ver producto
Tyrosine-Protein Kinase Receptor UFO (AXL) Antibody
AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11.Entrez Protein NP_001690.It is a member of the receptor tyro…
Ver producto
Tyrosine-Protein Kinase Receptor UFO (AXL) Antibody
Axl may function as a signal transducer between specific cell types of mesodermal origin.…
Ver producto