Mouse Tyrosine-Protein Kinase Mer (MERTK) Protein
819€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Tyrosine-Protein Kinase Mer (MERTK) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691225
tested applications
SDS-PAGE
Description
Mouse MERTK Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse MERTK (Q60805) extracellular domain (Met 1-Phe 498) was was fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Tyrosine-Protein Kinase Mer (MERTK) |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 79.3 kDa Sequence Fragment: Met1-Phe498 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q60805 |
| Gene ID | 17289 |
| Alias | MER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer |
| Background | Protein MERTK |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.
Related Products
Human Mer/MERTK(Tyrosine-protein kinase Mer) ELISA Kit
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
MERTK Antibody is a Rabbit Polyclonal antibody against MERTK.
Ver Producto
Tyrosine-Protein Kinase Mer (MERTK) Antibody
Rabbit polyclonal antibody against MERTK protein. Immunogen region is N-terminal.
Ver Producto