Mouse Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit

Este producto es parte de MERTK - MER proto-oncogene, tyrosine kinase
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715€ (96 tests)

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935106861
info@markelab.com
name
Mouse Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx516812
tested applications
ELISA

Description

Mouse Tyrosine-Protein Kinase Mer (MERTK) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Tyrosine-Protein Kinase Mer concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetTyrosine-Protein Kinase Mer (MERTK)
ReactivityMouse
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range78 pg/ml - 5000 pg/ml
Sensitivity< 40 pg/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ60805
Gene ID17289
AliasMER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer
BackgroundElisa kits for MERTK
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.

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