Mouse Transmembrane Emp24 Domain-Containing Protein 6 (TMED6) ELISA Kit
715€ (96 tests)
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Name
Mouse Transmembrane Emp24 Domain-Containing Protein 6 (TMED6) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx550424
Tested Applications
ELISA
Description
Mouse Transmembrane emp24 domain-containing protein 6 ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transmembrane emp24 domain-containing protein 6 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Transmembrane Emp24 Domain-Containing Protein 6 (TMED6) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9CQG0 |
| Gene ID | 66269 |
| Alias | PRO34237, SPLL9146, p24g5,p24 family protein gamma-5,p24gamma5 |
| Background | Elisa Kits for: TMED6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
TMED6 is a member of the p24 protein family, which regulates protein trafficking between the endoplasmic reticulum (ER), the ER-Golgi intermediate compartment (ERGIC), and the Golgi apparatus. TMED6 functions as a cargo receptor, facilitating the selection and packaging of secretory and membrane proteins into COPII-coated vesicles for ER export. It also participates in the retrieval of misfolded or redundant proteins back to the ER through COPI-mediated transport. TMED6 plays a role in maintaining proper protein quality control, ensuring efficient maturation and trafficking of proteins critical for cellular homeostasis. It is highly expressed in secretory tissues and immune cells, where it supports organelle organization, immune response modulation, and cellular communication. Dysregulation of TMED6 has been linked to metabolic disorders and cancers, where altered vesicle dynamics impair protein secretion and cellular growth. Knockdown studies reveal defects in protein trafficking, ER stress accumulation, and impaired Golgi organization, highlighting its role in secretory pathway regulation, protein homeostasis, and cellular integrity.
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