Mouse Transcription Factor E2F5 (E2F5) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for E2F5
proveedor
Abbexareference
abx520212Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Transcription Factor E2F5 (E2F5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transcription Factor E2F5 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
E2F5 is a transcriptional repressor that functions similarly to E2F4 in controlling cell cycle exit, quiescence, and differentiation. It forms complexes with pocket proteins such as p130 and p107 to repress proliferation-related genes, particularly during G0 and early G1 phases. E2F5 is highly expressed in non-proliferative and terminally differentiated cells, where it ensures proper tissue development and homeostasis. E2F5 plays a critical role in embryonic development, especially in the formation of the central nervous system, lungs, and cardiac tissues. Mutations in E2F5 have been linked to ciliopathies such as hydrocephalus, where impaired regulation of cilia-related genes disrupts fluid flow and tissue organization. Knockout studies reveal developmental defects, including hydrocephalus and improper cell cycle control, demonstrating E2F5’s importance in maintaining cellular quiescence, differentiation, and developmental stability.
Características del producto
category
ELISA Kits
immunogen target
Transcription Factor E2F5 (E2F5)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
E2F-5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
E2F5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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