Mouse Transcription Factor E2F4 (E2F4) ELISA Kit

Este producto es parte de E2F - E2F Transcription Factor
Mouse Transcription Factor E2F4 (E2F4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for E2F4

proveedor

Abbexa

reference

abx520210

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Transcription Factor E2F4 (E2F4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transcription Factor E2F4 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

E2F4 is a member of the E2F family that predominantly functions as a transcriptional repressor to regulate genes involved in cell cycle arrest and differentiation. Unlike E2F1-3, which activate proliferation-related genes, E2F4 associates with pocket proteins such as p107, p130, and RB to repress E2F target genes during quiescence (G0 phase) and early G1. It is highly expressed in differentiated and non-proliferative cells, where it helps maintain cellular homeostasis and tissue stability. E2F4 is essential for hematopoiesis, where it promotes the differentiation of erythroid and myeloid cells by suppressing proliferation signals. Dysregulation of E2F4 has been linked to cancers and developmental disorders due to disrupted cell cycle arrest mechanisms. Knockout models exhibit defects in hematopoiesis, impaired differentiation, and embryonic lethality, underscoring E2F4’s critical role in maintaining cellular quiescence, differentiation, and growth suppression.

Características del producto

category

ELISA Kits


immunogen target

Transcription Factor E2F4 (E2F4)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

E2F-4


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

E2F4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

anti- E2F4 antibody

anti- E2F4 antibody

proveedor

FineTest

reference

FNab02602

Tested Applications

ELISA, WB, IHC, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'...

Precio a consultar

Ver más

Recombinant Human E2F4

Recombinant Human E2F4

proveedor

FineTest

reference

P8113

Tested Applications

Western Blot, ELISA

status

RUO

Precio a consultar

Ver más

Transcription Factor E2F4 (E2F4) Antibody

Transcription Factor E2F4 (E2F4) Antibody

proveedor

Abbexa

reference

abx013064

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Rabbit polyclonal antibody against E2F4 protein. Immunogen region is Internal.

52€ (10 µg)

Ver más