Mouse Transcription Factor AP-2 Beta (TFAP2B) ELISA Kit

Este producto es parte de TFAP2 - Transcription factor AP-2 alpha
Mouse Transcription Factor AP-2 Beta (TFAP2B) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for TFAP2B

proveedor

Abbexa

reference

abx513146

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Transcription Factor AP-2 Beta (TFAP2B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Transcription factor AP-2-beta concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

TFAP2B, a member of the AP-2 transcription factor family, regulates gene expression by binding to GC-rich DNA sequences in promoter regions. It plays a key role in embryonic development, particularly in neural crest formation, cardiovascular system development, and kidney morphogenesis. TFAP2B contributes to cell proliferation, differentiation, and survival by controlling the transcription of genes involved in apoptosis, cell adhesion, and growth. Mutations in TFAP2B are associated with autosomal dominant Char syndrome, a congenital disorder characterized by heart defects, limb anomalies, and facial dysmorphisms. TFAP2B also plays a role in tumorigenesis, where its altered expression influences cell cycle progression, epithelial-mesenchymal transition (EMT), and metastasis in cancers such as breast and neuroblastoma. Knockout studies show developmental defects in cardiovascular structures and impaired neural crest cell migration, highlighting TFAP2B's essential role in organ development, tissue differentiation, and cell fate determination.

Características del producto

category

ELISA Kits


immunogen target

Transcription Factor AP-2 Beta (TFAP2B)


reactivity

Mouse


test range

1.56 ng/ml - 100 ng/ml


sensitivity

< 0.786 ng/ml


assay type

Competitive


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AP-2B,AP-2beta,AP2-B,PDA2,Activating enhancer-binding protein 2-beta


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

TFAP2B


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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