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Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Primary Antibodies
polyclonal
human,mouse,rat
transcription factor AP-2 beta(activating enhancer binding protein 2 beta)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IP
50 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000; IP: 1:200-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
TFAP2B
AP-2B,AP-2beta,AP2-B,PDA2,Activating enhancer-binding protein 2-beta
This product is for research use only.
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