Mouse Toll Like Receptor 1 (TLR1) Protein
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935106861
info@markelab.com
Precio
195€ (10 µg)
Protein TLR1
proveedor
Abbexareference
abx168804Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Mouse TLR1 Protein is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family, a critical component of the innate immune system that detects and responds to pathogens through pattern recognition. TLRs are integral to recognizing pathogen-associated molecular patterns (PAMPs), which are conserved molecular structures in microbes, such as bacterial cell wall components. TLR1, in particular, functions predominantly as a co-receptor with TLR2 and recognizes lipoproteins and lipopeptides derived from bacterial membranes. By binding these ligands, TLR1 initiates intracellular signaling pathways that activate pro-inflammatory cytokine production and immune cell recruitment, key processes for mounting an immune response against infection. TLR1 is primarily expressed on immune cells like monocytes, macrophages, dendritic cells, and neutrophils, and is involved in host defense against bacterial, fungal, and some viral pathogens. Its role in immune responses makes TLR1 a valuable focus for understanding immune signaling pathways and developing potential treatments for infections, inflammatory diseases, and cancers.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Toll Like Receptor 1 (TLR1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 42.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser25-Ile134 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
TLR1
dry ice
No
availability
Shipped within 5-7 working days.
alias
Toll-like receptor 1,TIL,CD281,rsc786,TIL. LPRS5,Toll/interleukin-1 receptor-like protein
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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