Human Toll Like Receptor 1 (TLR1) Protein

Este producto es parte de TLR1 - toll like receptor 1
Human Toll Like Receptor 1 (TLR1) Protein

Pida mas información

935106861

info@markelab.com

Precio

195€ (10 µg)

Protein TLR1

proveedor

Abbexa

reference

abx069356

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Toll Like Receptor 1 (TLR1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family, a critical component of the innate immune system that detects and responds to pathogens through pattern recognition. TLRs are integral to recognizing pathogen-associated molecular patterns (PAMPs), which are conserved molecular structures in microbes, such as bacterial cell wall components. TLR1, in particular, functions predominantly as a co-receptor with TLR2 and recognizes lipoproteins and lipopeptides derived from bacterial membranes. By binding these ligands, TLR1 initiates intracellular signaling pathways that activate pro-inflammatory cytokine production and immune cell recruitment, key processes for mounting an immune response against infection. TLR1 is primarily expressed on immune cells like monocytes, macrophages, dendritic cells, and neutrophils, and is involved in host defense against bacterial, fungal, and some viral pathogens. Its role in immune responses makes TLR1 a valuable focus for understanding immune signaling pathways and developing potential treatments for infections, inflammatory diseases, and cancers.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Toll Like Receptor 1 (TLR1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 32.5 kDa Observed MW: 31 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val114-Val339 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TLR1


dry ice

No


availability

Shipped within 5-7 working days.


alias

Toll-like receptor 1,TIL,CD281,rsc786,TIL. LPRS5,Toll/interleukin-1 receptor-like protein


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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