Mouse Toll Like Receptor 1 (TLR1) CLIA Kit
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Description
Mouse Toll Like Receptor 1 (TLR1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Toll Like Receptor 1 (TLR1) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.108 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Toll-like receptor 1,TIL,CD281,rsc786,TIL. LPRS5,Toll/interleukin-1 receptor-like protein |
| Background | CLIA Kits TLR1 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family, a critical component of the innate immune system that detects and responds to pathogens through pattern recognition. TLRs are integral to recognizing pathogen-associated molecular patterns (PAMPs), which are conserved molecular structures in microbes, such as bacterial cell wall components. TLR1, in particular, functions predominantly as a co-receptor with TLR2 and recognizes lipoproteins and lipopeptides derived from bacterial membranes. By binding these ligands, TLR1 initiates intracellular signaling pathways that activate pro-inflammatory cytokine production and immune cell recruitment, key processes for mounting an immune response against infection. TLR1 is primarily expressed on immune cells like monocytes, macrophages, dendritic cells, and neutrophils, and is involved in host defense against bacterial, fungal, and some viral pathogens. Its role in immune responses makes TLR1 a valuable focus for understanding immune signaling pathways and developing potential treatments for infections, inflammatory diseases, and cancers.
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