935106861
info@markelab.com
Precio
687.5€ (96 tests)
Mouse TNF receptor-associated factor 5 (TRAF5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse TNF receptor-associated factor 5 concentrations in tissue homogenates, cell lysates and other biological fluids.
TRAF5 is a signaling adaptor protein that mediates pathways downstream of TNF receptors (TNFR), CD40, and BAFF-R, activating NF-κB and JNK to regulate inflammation, immune cell activation, and survival. TRAF5 plays a critical role in adaptive immune responses, particularly in T and B cell activation, cytokine production, and lymphoid tissue development. It works redundantly with TRAF2 to promote canonical NF-κB activation, ensuring appropriate immune responses to inflammatory and survival signals. TRAF5 is widely expressed in immune cells and epithelial tissues, where it supports cellular signaling during infections and tissue repair. Dysregulation of TRAF5 contributes to autoimmune diseases and inflammatory conditions, where altered NF-κB signaling enhances cytokine production and immune cell proliferation. Knockout studies reveal defects in lymphocyte activation, impaired cytokine signaling, and altered immune responses, highlighting its importance in immune regulation and inflammatory signaling.
ELISA Kits
TNF receptor-associated factor 5 (TRAF5)
Mouse
0.156 ng/ml - 10 ng/ml
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
TRAF-5,TRAF5, MGC:39780, RNF84, TNF receptor associated factor 5
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
TRAF5
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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