Mouse Tissue Factor Pathway Inhibitor 2 (TFPI2) Protein

Este producto es parte de TFPI - Tissue factor pathway inhibitor
Mouse Tissue Factor Pathway Inhibitor 2 (TFPI2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein TFPI2

proveedor

Abbexa

reference

abx069326

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant TFPI2 is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Tissue Factor Pathway Inhibitor 2 (TFPI2), another Kunitz-type inhibitor, is structurally similar to TFPI but exhibits distinct functions, primarily inhibiting plasmin and matrix metalloproteinases (MMPs). TFPI2 plays a critical role in modulating extracellular matrix degradation, cell migration, and angiogenesis, influencing processes like wound healing, tissue remodeling, and tumor progression. Unlike TFPI, TFPI2 is broadly expressed in various tissues and is frequently downregulated in cancers, where its loss contributes to tumor invasion, metastasis, and angiogenesis. Its epigenetic silencing through promoter hypermethylation is a hallmark in several malignancies, highlighting its potential as a tumor suppressor and biomarker for cancer diagnosis and prognosis.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Tissue Factor Pathway Inhibitor 2 (TFPI2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 25.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu23-Ser230 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TFPI2


dry ice

No


availability

Shipped within 5-12 working days.


alias

PP5,REF1,TFPI-2,Placental protein 5


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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reference

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reactivity

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status

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clonality

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