Mouse Thrombopoietin receptor (MPL) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits MPL
proveedor
Abbexareference
abx550933Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Thrombopoietin receptor (MPL) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Thrombopoietin receptor concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
MPL, also known as the thrombopoietin receptor, is a critical component in hematopoiesis, particularly for the regulation and production of platelets. It is the cellular receptor for thrombopoietin (TPO), a hormone produced primarily by the liver that promotes the proliferation and maturation of megakaryocytes, the precursors to platelets. MPL is a member of the type I cytokine receptor family and is essential for maintaining platelet counts within physiological ranges. Its activity regulates not only the production of platelets but also has implications in stem cell maintenance and self-renewal within the hematopoietic system. MPL is encoded by the MPL gene located on chromosome 1 (1p34) in humans. Mutations in this gene are associated with various myeloproliferative disorders and hematological diseases, including essential thrombocythemia, primary myelofibrosis, and certain leukemias. Due to its central role in platelet production and stem cell maintenance, MPL is a significant focus of research for understanding hematopoietic disorders and developing targeted therapies.
Características del producto
category
ELISA Kits
immunogen target
Thrombopoietin receptor (MPL)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
MPL proto-oncogene, MPLV,TPOR,C-MPL,CD110,THPOR,THCYT2,PO-R,Myeloproliferative leukemia protein,Proto-oncogene c-Mpl
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
MPL
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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