Mouse Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) ELISA Kit

Este producto es parte de SART - Squamous Cell Carcinoma Antigen Recognized By T-Cell
Mouse Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) ELISA Kit
715€ (96 tests)

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Name
Mouse Squamous cell carcinoma antigen recognized by T-cells 3 (SART3) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx390643
Tested Applications
ELISA

Description

Mouse Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse SART3 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
78 pg/ml - 5000 pg/ml
Sensitivity
< 35.0 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q9JLI8
Gene ID
53890
Alias
DSAP1,P100,RP11-13G14,TIP110,p110,p110(nrb)Tat-interacting protein of 110 kDa
Background
Elisa Kits for: SART3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Spliceosome associated factor 3, U4/U6 recycling protein (SART3) is a multifunctional protein that plays a critical role in the recycling of U4/U6 snRNPs during spliceosome disassembly SART3 ensures the efficient reassembly of U4/U6 complexes, which are required for the next round of pre-mRNA splicing, maintaining the fidelity and efficiency of gene expression Beyond its role in splicing, SART3 interacts with RNA-binding proteins and participates in the regulation of alternative splicing, influencing proteomic diversity SART3 is also implicated in the regulation of telomerase activity and cellular senescence, linking its function to genome stability Dysregulation of SART3 has been associated with cancers and autoimmune diseases, where abnormal RNA splicing contributes to altered gene expression and disease progression Recent studies suggest that SART3 interacts with viral RNAs during infections, regulating host-pathogen interactions and immune responses Its role in RNA metabolism, spliceosome recycling, and genome integrity highlights its importance in maintaining cellular function and gene regulation pathways

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